On August 27th, 2016 BlastphamousHD tweeted this: https://twitter.com/BlastphamousM/status/769664383077142528 This tweet explains that BHD has indeed broken up with Dr.Girlfriend. In other tweets he described how the two homies were still "cool" and that although this they are friends, she may not be in his videos for a while. Although he has tweeted about the possibility creating a video on the matter, we have yet to see his official explanation.
UPDATE-This video further explains the matter-
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UPDATE- On November 11th, 2016 BHD released a video confirming he, and Dr. Girlfriend were back together.